My biggest enemy is clutter.
I keep my house fairly clean. I make sure surfaces are wiped down in the kitchen and bathrooms regularly, I vacuum weekly, I dust - all the things we're taught to do when we're growing up. But I don't enjoy it because its thankless work with no real reward. No one walks into a house and says "Oh your house looks so clean!"
So I keep it clean so its healthy and livable, but my real nemesis is clutter. I have a hard time keeping up with the clutter. It just seems as though things multiply around the house on tables and counter tops. There's the mail I still need to sort, the bills I still need to pay, the files for the various committees I'm working on, and things I need to take to the dump....just clutter.
I need to continually de-clutter my house. I guess I need to do the same with my mind. I'm working on that right now too!